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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX10
All Species:
20.61
Human Site:
S267
Identified Species:
41.21
UniProt:
O75333
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75333
NP_005986.2
385
42341
S267
V
A
P
R
P
L
L
S
V
P
A
R
S
H
S
Chimpanzee
Pan troglodytes
XP_001152773
385
42344
S267
V
A
P
R
P
L
L
S
V
P
A
R
S
H
S
Rhesus Macaque
Macaca mulatta
XP_001117884
385
42153
S267
V
A
P
Q
P
L
L
S
V
P
A
R
S
H
S
Dog
Lupus familis
XP_854616
415
46118
S298
V
S
S
R
T
L
L
S
I
P
A
R
S
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q810F8
385
42389
S267
V
T
P
R
P
L
L
S
I
P
A
R
S
R
S
Rat
Rattus norvegicus
Q5I2P1
517
57726
T369
G
L
S
T
S
Y
R
T
E
S
A
Q
R
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8UW76
440
48669
S296
I
E
R
E
S
V
E
S
L
I
Q
K
H
S
Y
Frog
Xenopus laevis
Q32NI9
463
51134
L312
R
N
H
R
P
G
S
L
P
L
M
N
A
F
A
Zebra Danio
Brachydanio rerio
Q8AXX2
460
51532
L309
R
N
H
R
P
G
S
L
Q
I
M
S
A
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
N528
K
K
Q
A
L
M
S
N
R
G
S
D
S
D
K
Honey Bee
Apis mellifera
XP_624689
391
43181
S283
I
T
Q
L
K
I
A
S
N
P
F
A
K
G
F
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
D261
Q
L
H
R
M
N
G
D
A
T
Q
S
P
P
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
77.1
N.A.
82
35
N.A.
N.A.
35
53.1
50.6
N.A.
22.7
44.7
35.4
N.A.
Protein Similarity:
100
99.2
97.4
80.9
N.A.
87.7
46.6
N.A.
N.A.
48.8
62.8
61.7
N.A.
29.4
56.2
51.2
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
80
6.6
N.A.
N.A.
6.6
13.3
13.3
N.A.
6.6
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
86.6
26.6
N.A.
N.A.
33.3
26.6
26.6
N.A.
26.6
26.6
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
9
0
0
9
0
9
0
50
9
17
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
9
0
9
0
% D
% Glu:
0
9
0
9
0
0
9
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
17
9
% F
% Gly:
9
0
0
0
0
17
9
0
0
9
0
0
0
9
9
% G
% His:
0
0
25
0
0
0
0
0
0
0
0
0
9
25
0
% H
% Ile:
17
0
0
0
0
9
0
0
17
17
0
0
0
0
0
% I
% Lys:
9
9
0
0
9
0
0
0
0
0
0
9
9
0
9
% K
% Leu:
0
17
0
9
9
42
42
17
9
9
0
0
0
0
0
% L
% Met:
0
0
0
0
9
9
0
0
0
0
17
0
0
0
0
% M
% Asn:
0
17
0
0
0
9
0
9
9
0
0
9
0
0
0
% N
% Pro:
0
0
34
0
50
0
0
0
9
50
0
0
9
17
0
% P
% Gln:
9
0
17
9
0
0
0
0
9
0
17
9
0
9
0
% Q
% Arg:
17
0
9
59
0
0
9
0
9
0
0
42
9
9
0
% R
% Ser:
0
9
17
0
17
0
25
59
0
9
9
17
50
9
42
% S
% Thr:
0
17
0
9
9
0
0
9
0
9
0
0
0
0
0
% T
% Val:
42
0
0
0
0
9
0
0
25
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _